Large-scale genome-wide association analysis reveals candidate genes in yak body size traits.

ABSTRACT:

Background

The yak is a unique livestock species bred on the Qinghai-Tibet Plateau. We utilized genotypic data obtained from the yak sequencing chip "Qingxin-1" and phenotypic data measured from image photographs using conversion between pixel and distance. The primary objective of this study was to conduct genome-wide association studies (GWAS) using five models to analyze seven body size traits. Specifically, the goals were to (1) characterize the genetic structure of three major yak breeds: Maiwa, Yushu, and Huanhu; (2) identify candidate genes that significantly influence yak body size traits; and (3) compare the prediction accuracy of single-trait and multi-trait genomic selection(GS).

Results

A total of 94 markers were significantly (P<1e-05) associated with yak body s

SUBMITTER: Zhao J 

PROVIDER: S-EPMC12465381 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature