Effect of acute kidney injury care bundles on patient prognosis: a systematic review and meta-analysis.

ABSTRACT:

Background

Acute kidney injury (AKI) is a severe complication among hospitalized patients. This study aimed to investigate the effect of care bundles on the prognosis of AKI patients.

Methods

Electronic databases were searched from January 2012 to December 2023. Randomized controlled trials and cohort studies evaluating the effect of AKI care bundles were included. A meta-analysis using a random-effects model was conducted to explore the efficacy of the AKI care bundle.

Results

A total of 12 studies with 30,152 participants were included. Based on the random-effects model, the AKI care bundles significantly improved the AKI severity (RR: 0.77, 95% CI: 0.60-0.98, I² = 64%) and the need for renal replacement therapy (RR: 0.66, 95% CI: 0.46-0.94, I²

SUBMITTER: Huang Y 

PROVIDER: S-EPMC12465485 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature