Exploring the incidence potential of phenol-soluble modulins among methicillin-resistant Staphylococcus aureus in Lahore, Pakistan.

ABSTRACT:

Background

Methicillin-resistant Staphylococcus aureus (MRSA) has emerged as a major clinical and epidemiological problem over the past few decades. This study aimed to investigate antibiotic resistance patterns, incidence potential of phenol-soluble modulins (PSMs) genes and explored the associations between miscellaneous clinical specimens of MRSA and the incidence of virulent PSMs genes.

Methods

This investigation employed a total of sixty MRSA strains isolated from clinical specimens such as pus aspirates, wound swabs, ear swabs, tissue swabs, blood, and urine. Antibiotic profiling was performed via Kirby-Bauer (KB) disk diffusion method. Genetic analysis was performed for detection of S. aureus-specific 16SrRNA gene, methicillin-resistant mecA and its homologue mecC gen

SUBMITTER: Mudassar S 

PROVIDER: S-EPMC12465548 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature