Association between uric acid to high-density lipoprotein cholesterol ratio (UHR) and female infertility: insights from a cross-sectional study.

ABSTRACT:

Background

Infertility in women of reproductive age is a major worldwide health problem. Oxidative stress, inflammatory responses, and dysregulation of lipid metabolism are among the factors that contribute to female infertility. The ratio of serum uric acid to high-density lipoprotein cholesterol (UHR), a novel composite biomarker that reflects oxidative stress and lipid metabolism, has not been extensively studied in relation to female infertility. This study aims to explore the associations between UHR levels and female infertility.

Methods

This cross-sectional study focused on females aged 18-44 years in the National Health and Nutrition Examination Survey from 2013 to 2018. The association between UHR and infertility was assessed by weighted multivariable logistic regre

SUBMITTER: Wang J 

PROVIDER: S-EPMC12465579 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature