Opportunistic screening of osteoporosis in lung transplant recipients: diagnostic value of pre-transplant thoracic CT using vertebral Hounsfield units.

ABSTRACT:

Purpose

To evaluate the diagnostic performance of pre-transplant chest computed tomography (CT) as an opportunistic screening tool for predicting osteoporosis 1 year after lung transplantation.

Method

We retrospectively enrolled lung transplant patients from a tertiary center in Zhejiang, China, between September 2022 and December 2023. Standardized regions of interest were placed on the first thoracic vertebra (T1) through the first lumbar vertebra (L1) to measure CT-derived Hounsfield unit (HU) values. Patients were categorized into normal BMD, osteopenia, and osteoporosis groups on the basis of their baseline dual-energy X-ray absorptiometry (DEXA) T-scores. Clinical baseline characteristics and HU values were compared among the three groups. The correlation between pre-t

SUBMITTER: Zeng F 

PROVIDER: S-EPMC12465804 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature