Treatment outcomes for drug-resistant tuberculosis: a retrospective longitudinal study.

ABSTRACT:

Background

This study examined the treatment outcomes of multidrug-resistant tuberculosis (MDR-TB) in Kazakhstan, where its burden is notably high.

Methods

The authors conducted a retrospective longitudinal study using the National Tuberculosis Registry, this study analyzed treatment outcomes in MDR-TB patients from 2018 to 2021, and included adult patients (≥ 18 years) who completed a specific treatment. Outcomes were categorized into successful and unsuccessful treatments. Bivariate and multivariate Poisson regression models with modified errors were employed to obtain crude and adjusted risk ratios (aRR).

Results

The study cohort comprised 12,698 cases, of which 10, 306 (81.16%) completed treatment with a successful outcome, while 2,392 (18.84%) had unsuccessful ou

SUBMITTER: Akhmedullin R 

PROVIDER: S-EPMC12466029 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature