The additive effect of cardiopulmonary fitness and triglyceride-glucose index on the risk of metabolic syndrome.

ABSTRACT:

Background

Metabolic syndrome (MetS) is a cluster of risk factors including increased triglycerides, insulin resistance, and hypertension, posing increasing public health challenges. Both cardiorespiratory fitness (CRF) and the Triglyceride-Glucose (TyG) index have been associated with MetS risk independently. However, their combined predictive value remains unclear. This study aims to assess the combined influence of CRF and TyG index on MetS risk in a survey sample.

Methods

Data from 3742 participants in the National Health and Nutrition Examination Survey (NHANES) in year cycle of 1999-2004 were analyzed. Logistic regression and restricted cubic spline (RCS) analyses were used to evaluate the associations of CRF and TyG index with MetS risk. Subgroup analyses by different

SUBMITTER: Li M 

PROVIDER: S-EPMC12466076 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature