Lance-Adams Syndrome: An Updated Review of a Rare Post-Hypoxic Complication.

ABSTRACT:

Objectives

This review aims to provide a comprehensive understanding of Lance-Adams Syndrome (LAS), focusing on its pathophysiology, diagnosis, management, and patient outcomes.

Methods

Utilizing the PICO framework, articles describing known cases of LAS and interventions were included, with no specific comparisons. The search was conducted in Google Scholar, PubMed, and Scopus databases.

Results

LAS is characterized by action myoclonus and related symptoms. Imbalances in neurotransmitters and involvement of brain areas like the cerebellum, thalamus, and basal ganglia play a role in its pathophysiology. Diagnosis primarily relies on symptom history post-anoxic events, and treatments vary in effectiveness. LAS generally carries a more favorable functional prognosis tha

SUBMITTER: Malakooti M 

PROVIDER: S-EPMC12466330 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature