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Assessment of Antimicrobial Resistance and Virulence of Biofilm-Forming Uropathogenic <i>Escherichia coli</i> from Rio de Janeiro.


ABSTRACT: Background/Objectives: Uropathogenic Escherichia coli (UPEC) is the leading cause of urinary tract infections in both community and hospital settings worldwide. Antimicrobial-resistant UPEC strains pose a significant challenge for effective antibiotic therapy. In this study, 50 bacterial isolates recovered from urine samples of patients attended in different sectors of a public hospital in Rio de Janeiro over five months were analyzed to assess antimicrobial resistance and virulence profiles through broad gene screening. Methods: Biofilm production was assessed using a semi-quantitative adherence assay. PCR was employed to investigate 27 resistance genes, 6 virulence genes, sequence types (STs), and phylogroups. Susceptibility to 25 antimicrobial agents was determined

SUBMITTER: Oliveira MCF 

PROVIDER: S-EPMC12466447 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature