Effectiveness of gamma-oryzanol in glycaemic control and managing oxidative stress, inflammation, and dyslipidaemia in diabetes: a systematic review of preclinical studies.

ABSTRACT:

Background

Diabetes mellitus (DM) and associated complications remain a global public health challenge despite many confrontational aspects of the disease, and its prevalence is projected to rise in the coming decades. Thus, there is an urgent need to intensify the current efforts to address both the prevalence and adverse effects of diabetes, including the use of natural products. Increasing evidence from the scientific literature has revealed the beneficial effects of gamma oryzanol for treating diabetes and its related complications.

Aim

To investigate the effectiveness of gamma oryzanol (γ-oryzanol) in managing hyperglycaemia, oxidative stress, inflammation, and dyslipidaemia in a rodent model of diabetes mellitus.

Methodology

The review was conducted by searching

SUBMITTER: Radda MI 

PROVIDER: S-EPMC12466496 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature