Modalities Differentiation of Pain Perception Following Ischemic Stroke: Decreased Pressure Pain Perception.

ABSTRACT: Background/Objectives: Ischemic stroke frequently leads to somatosensory impairments and abnormal pain perception. Meanwhile, pain perception can be evoked through multiple somatosensory modalities, each mediated by distinct neural pathways. Despite this understanding, current research investigating stroke-induced alterations in pain perception across different modalities of noxious stimulation remains insufficient, particularly concerning responses to varying stimulus intensities (including both sub-threshold and supra-threshold levels). Methods: In this study (March 2023 to July 2024), we enrolled 30 ischemic stroke patients and 35 matched controls and employed two modalities of noxious stimuli (e.g., heat stimuli were delivered using the Medoc CHEPS and pressure stimuli we

SUBMITTER: Zhi Y 

PROVIDER: S-EPMC12466989 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature