Prior Aerobic Exercise Training Fails to Confer Cardioprotection Under Varying Exercise Volumes in Early Post-Infarction Cardiac Remodeling in Female Rats.

ABSTRACT: Background: There is no information on how the dose of exercise training prior to myocardial infarction (MI) affects cardioprotection. Objective: This study aimed to evaluate the cardioprotective role of different volumes of exercise training prior to MI. Methods: Wistar female rats were allocated to one of the following groups: SHAM (not trained and undergoing simulated MI surgery), NT+MI (untrained and undergoing MI surgery), T60+MI (trained 60 min per session and undergoing MI surgery), T90+MI (trained 90 min per session and undergoing MI surgery), and T180+MI (trained 180 min per session and undergoing MI surgery). The training protocol was performed in a swimming pool for eight weeks. On the seventh day after MI, the animals underwent left ventricular (LV) structu

SUBMITTER: Dias ARL 

PROVIDER: S-EPMC12467140 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature