Chemical Composition of Clove and Fennel Seed Essential Oils and a Comparison of Their <i>In Silico</i> and <i>In Vitro</i> Antibacterial Activity with That of Their Main Compounds.

ABSTRACT: This study aimed to assess the chemical composition and antibacterial potential of essential oils (EOs) from two plants: clove buds (Syzygium aromaticum) and fennel seeds (Foeniculum vulgare) EOs. The major compounds, eugenol and estragole, were isolated from these oils and tested against Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa. The EOs were obtained via hydrodistillation and analyzed using Gas Chromatography-Mass Spectrometry (GC-MS). Clove oil was found to be rich in eugenol (68.51%), while fennel seed oil was dominated by estragole (93.30%). Antibacterial activity, assessed by the agar disc diffusion method and supported by MIC/MBC testing, revealed that eugenol exhibited the highest efficacy, with MIC values ranging from 0.

SUBMITTER: Abdou A 

PROVIDER: S-EPMC12468443 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature