Personal approach for cancer treatment: A meta-analysis of Phase II clinical trials.

ABSTRACT:

Background

To date, no meta-analysis has studied the general outcomes of personalized cancer drug therapy with a focus on current targeted, immunotherapy, and multi-agent phase II clinical trials.

Objective

We conducted a systematic review and meta-analysis to provide a comprehensive overview of outcomes in patients undergoing personalized genomics-based versus non-personalized treatment in oncology.

Data source

We searched for publications in PubMed, dedicated to specific cancer drug treatment and phase II clinical trials, and published from 2010 to 2021. The search dates were from 20.10.23 to 20.11.23. The final data check was on 20.12.23.

Selection criteria

Studies of chemotherapy, immunotherapy, and targeted therapy were included. Only trials, including adu

SUBMITTER: Potievskiy MB 

PROVIDER: S-EPMC12469113 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature