Multidimensional Regulatory Mechanisms of <i>LvChia2</i> on Growth in the Pacific White Shrimp (<i>Litopenaeus vannamei</i>).

ABSTRACT: Background: As a globally significant aquaculture species, elucidating the molecular mechanisms underlying the regulation of the Pacific White Shrimp (Litopenaeus vannamei) growth holds substantial scientific and industrial value. This study systematically investigates the role of the LvChia2 gene in governing growth and development through a cross-tissue metabolic network approach. Methods: RNA knockdown (RNAi)-mediated knockdown of LvChia2 significantly impaired growth performance and triggered a tissue-specific metabolic compensation mechanism. Results: This mechanism was characterized by reduced crude lipid content in muscle and adaptive modulation of lipase (LPS) activities in hepatopancreatic and intestinal tissues, suggesting inter-tissue me

SUBMITTER: Li S 

PROVIDER: S-EPMC12470064 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature