Genetic Diversity and Selection of <i>MHC I-UAA</i> in Clariid Catfish from Thailand: Implications for Breeding and Conservation.

ABSTRACT: Background/Objectives: Understanding variabilities in the Major Histocompatibility Complex class I (MHC I) gene is essential for evaluating immunogenetic diversity in clariid catfish. MHC I plays a critical role in immune defense by presenting endogenous antigens to cytotoxic T cells. Therefore, we aimed to investigate the genetic diversity, selection patterns, and phylogenetic relationships of MHC I alleles in three important clariid catfish species (Clarias gariepinus, Clarias macrocephalus, and Clarias batrachus) across wild and hatchery populations in Thailand. Methods: Targeted next-generation sequencing of a 174 bp fragment partial exon 6 of MHC I-UAA gene was performed, along with phylogenetic analyses, neutrality tests

SUBMITTER: Nguyen THD 

PROVIDER: S-EPMC12470123 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature