Effect of Sunlight-Induced Isomerisation on the Biotransformation of 4'-Hydroxychalcones by <i>Yarrowia lipolytica</i> KCh 71.

ABSTRACT: This study investigates the impact of light exposure on the biotransformation of chalcones in yeast cultures. 4'-Hydroxychalcones, with a hydroxyl group in the A-ring, are characteristic substrates efficiently converted into 4'-hydroxydihydrochalcones-compounds naturally occurring in medicinal plants such as Glycyrrhiza glabra (licorice), Stevia rebaudiana, and Angelica keiskei (ashitaba). These compounds are valued for their bioactivity and are relevant to natural product research. In this research, we present the outcomes of the selective microbial reduction of chalcones to dihydrochalcones using the yeast Yarrowia lipolytica KCh 71, cultivated under both light and dark conditions. The aim was to determine whether light exposure affects the efficiency or selec

SUBMITTER: Chlipala P 

PROVIDER: S-EPMC12470138 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature