Pulmonary <i>Verruconis</i> Infection in an Immunocompetent Patient: A Case Report and Literature Review.

ABSTRACT: Verruconis species are thermophilic, darkly pigmented fungi commonly found in hot environments. Despite their environmental ubiquity, fewer than fifty human infections have been reported, with V. gallopava responsible for most cases. While infections primarily occur in immunocompromised individuals, only six cases in immunocompetent patients have been documented. We describe a case of pulmonary Verruconis infection in a 75-year-old immunocompetent woman. Despite broad-spectrum antifungal treatments, including liposomal amphotericin B and voriconazole, the patient's condition deteriorated. Bronchoalveolar lavage (BAL) revealed hyphal forms, and fungal culture identified a Verruconis species. Antifungal susceptibility tests showed low minimal inhibitory concentrat

SUBMITTER: Xu L 

PROVIDER: S-EPMC12471020 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature