Inflammation, Autonomic Control, and Adiposity in Adolescents: Links to Early Cardiovascular Risk.

ABSTRACT: Cardiovascular diseases (CVDs) are generally associated with adulthood, although the underlying processes may begin in childhood and adolescence. Thus, detecting increased cardiovascular risk in adolescence is essential for prevention. In this cross-sectional study, we comprehensively evaluated the inter-relationships between inflammatory markers, cardiac autonomic control indexed by heart rate variability (HRV), and adiposity measures in healthy adolescents, with sex-stratified analyses. We examined 90 adolescents (55 females; age 15.8 ± 1.5 years; BMI 21.4 ± 3.3 kg/m²). We found mixed (positive and negative) associations between inflammatory markers and HRV indices among the entire adolescent group (absolute r range: 0.266-0.395, p < 0.05 for all), while only negative a

SUBMITTER: Micieta V 

PROVIDER: S-EPMC12471339 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature