Effects of Waxy Maize Starch and Malate-Debranched Waxy Maize Starch on Gut Microbiota of Humans In Vitro and Mice In Vivo.

ABSTRACT: The gut microbiota plays a pivotal role in host health. Dietary components such as waxy maize starch (WMS) and malate-debranched WMS (MADBS) may serve as modulators of microbial composition and function. In this study, the effects of WMS and MADBS on murine gut microbiota in vivo and human fecal in vitro fermentation were investigated. The results of gut microbiota in mice revealed that WMS increased the abundance of Muribaculaceae and Bifidobacterium, while MADBS enriched Ileibacterium, Muribaculaceae, and Dubosiella. The in vitro fermentation model demonstrated that WMS increased the abundance of Bifidobacterium, Lactobacillus, Megamonas, and Megasphaera, whereas MADBS enhanced Weissella, Lactobacillus, and P

SUBMITTER: Zhao Z 

PROVIDER: S-EPMC12472379 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature