Antimicrobial Activity and Potential of Olive Leaf Extract as a Topical Agent to Combat <i>Staphylococcus aureus</i> and MRSA Strains: An In Vitro Evaluation.

ABSTRACT: Background: Staphylococcus aureus is one of the most prevalent bacteria in skin and soft tissue infections (SSTIs). Multidrug-resistant strain emergence, particularly methicillin-resistant S. aureus (MRSA), highlights the need for alternative treatments. Objectives: This study investigates the antimicrobial properties of olive leaf extract (OLE) and describes an epidemiological profiling of patients with SSTI who may benefit from it. Methods: OLE was tested in two reference strains, methicillin-susceptible S. aureus (MSSA) ATCC 29213 and MRSA ATCC 700699, and in 126 clinical isolates from patients with SSTIs according to Clinical Laboratory Standards Institute guidelines. Results: The minimum bactericidal concentration (MBC) ranged from 3.12

SUBMITTER: Clusa L 

PROVIDER: S-EPMC12472457 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature