Ultrasound-Assisted Eutectic Solvent-Based Process Intensification for Sustainable Recovery of Oleuropein from Olive Leaves.

ABSTRACT: Olive leaves, a significant source of agri-food waste, can be valorized as feedstock in biorefineries due to their high content of antioxidant compounds, mainly polyphenols. This study aims to valorize olive leaves through an efficient solid/liquid extraction of oleuropein, its main polyphenol, using green solvents and advanced technologies. Accordingly, three natural eutectic solvents formed with 1,2-butanediol and choline chloride, betaine, or proline, which incorporated water or ethanol as cosolvents, and ultrasound-assisted extraction to enhance the process were used in this work. Additionally, the effect of the cosolvent composition on the physical properties of the solvent mixtures (i.e., density and viscosity as a function of temperature) was evaluated. The extraction time was optim

SUBMITTER: Sanchez-Monedero A 

PROVIDER: S-EPMC12472559 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature