Impact of Organic and Conventional Husbandry Systems on the Gut Microbiome and Resistome in Pigs.

ABSTRACT: The gut microbiome of pigs is important for energy supply and impacts the animals' health. Additionally, the microbiota can act as a reservoir for antimicrobial resistance genes (ARG). Different husbandry systems in pig farming can influence the microbiome and the overall composition of the resistome, i.e., the complete collection of ARG. In this study, pooled fecal samples were collected repeatedly in one pig farm over a period of two years. One group of animals was kept in organic husbandry conditions with access to an outdoor run, while the other group was kept according to conventional standards. Shotgun metagenomic sequencing was performed on the samples. Additionally, E. coli isolates were subjected to whole-genome sequencing and antimicrobial susceptibility testing. Significa

SUBMITTER: Wedemeyer J 

PROVIDER: S-EPMC12472612 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature