Correlation Study on Antibiotic Resistance and Antibacterial Activity of Soil Microorganisms in Lop Nur.

ABSTRACT: Lop Nur, an extremely arid environment, harbors unique microbial resources and represents a potential reservoir for novel bioactive substances. With antibiotic resistance becoming an increasing global concern, the resistance traits of microorganisms in extreme habitats and their potential association with antibacterial activity remain poorly understood. This study aimed to investigate the diversity of soil microorganisms in Lop Nur, their resistance to norfloxacin, kanamycin, and amoxicillin, and their inhibitory activity against common pathogenic bacteria, thereby providing a scientific basis for the discovery of new antibacterial candidates. Surface soils from three sampling points in Lop Nur were inoculated onto Gao's No.1 and LB media supplemented with different antibiotic regimens (si

SUBMITTER: Wen F 

PROVIDER: S-EPMC12472750 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature