Longitudinal Trend in Hospital-Wide Syphilis Testing and Clinical Characteristics of Syphilis Requiring Treatment.

ABSTRACT: Globally, syphilis cases are rising, and varied symptoms hinder diagnosis, highlighting the role of serological testing. Comprehensive institutional analysis is needed, as many reports are limited. We retrospectively reviewed 23 persons with syphilis treated at Kanazawa University Hospital (January 2007-December 2023). Of 9145 individuals tested for treponemal (chemiluminescent enzyme immunoassay) and nontreponemal (rapid plasma reagin, RPR) antibodies, diagnoses were based on clinical assessment and serology. Data on history, stage, lesions, and treatment were collected. From 2007 to 2023, antibody testing increased, but treated cases stayed stable (0-4/year). Males comprised 60.9% and females 39.1%. In the treated 23 patients, ophthalmology (30.4%) and dermatology (17.4%) accounted for n

SUBMITTER: Takemori-Sakai Y 

PROVIDER: S-EPMC12472834 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature