Zinc Oxide Nanoparticles Affect the Genomic and Redox Status of Chicken Embryo-Influence of Shape.

ABSTRACT: With the spread of nanotechnology use in industry, exposure to nanomaterials is currently exponentially increasing. With reports indicating nanoparticles' ability to pass through key biological barriers-gastrointestinal, lung, skin, blood-brain and the placenta barriers-the question of their safety, particularly the risks associated with embryonic development, arises. The aim of this article is to verify the impact of ZnO nanoparticles, which are commonly used and considered to be safe for adult organisms on the developing embryo. In the current study, the influence of the dose and shape of ZnO nanoparticles (oval vs. long) was evaluated in the chicken embryo model. The oxidative stress (superoxide dismutase (SOD)) activity, malondialdehyde (MDA) and carbonylated protein ((CP) levels), and

SUBMITTER: Dominiak B 

PROVIDER: S-EPMC12472910 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature