In Vitro Suppression Effects of <i>Ephedra przewalskii</i> Stapf-Derived Natural Compounds on SARS-CoV-2.

ABSTRACT:

Background

Ephedra przewalskii Stapf stems are a traditional Mongolian medicine commonly used to treat infectious diseases. Previous in vitro experiments have shown that the extract powder derived from its stems possesses antiviral activity. However, the active compounds responsible for this activity in E. przewalskii Stapf have not yet been identified or evaluated. This study aimed to identify the active components in E. przewalskii that exhibit antiviral effects against SARS-CoV-2 in vitro and validate their antiviral activity.

Methods

E. przewalskii stem extracts were subjected to high-performance liquid chromatography with varying methanol ratios in the mobile phase to obtain fractions with different polarities. Antiviral activity was assessed

SUBMITTER: Zhu X 

PROVIDER: S-EPMC12473021 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature