Chemical Composition and Bioactivity of Essential Oils from <i>Magnolia pugana</i>, an Endemic Mexican Magnoliaceae Species.

ABSTRACT: Magnolia pugana (Iltis & A. Vazquez) A. Vázquez & Carvajal, an endemic Mexican species of the Magnoliaceae family, has received limited phytochemical and pharmacological attention. This study reports, for the first time, the chemical composition and in vitro bioactivities of essential oils (EOs) obtained from its leaves, flowers, and seeds. EOs were analyzed by gas chromatography-mass spectrometry (GC-MS) and flame ionization detection (GC-FID), revealing cyclocolorenone, a sesquiterpene, as the major compound (38-40%) across all plant parts. Antioxidant activity was evaluated using DPPH• and ABTS• radical scavenging assays, complemented by bioautographic thin-layer chromatography (TLC). Antibacterial activity was determined by minimum inhibitory concentration (MIC) against human pa

SUBMITTER: Osorio E 

PROVIDER: S-EPMC12473070 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature