<i>OsLAC12</i>, a Laccase-Encoding Gene, Contributes to Rice Heat Tolerance Through Regulation of Antioxidant Defense and Secondary Metabolism.

ABSTRACT: Heat stress (HT) exerts significant negative impacts on plant growth, development, and productivity. In this study, we identified OsLAC12, a heat-induced laccase-encoding gene, as a key regulator of heat tolerance in rice. Functional validation confirmed that OsLAC12 encodes an active laccase, with supporting evidence showing that roots of OsLAC12 overexpression lines exhibited ~1.5-fold higher laccase activity and nearly three times the lignin content compared to the wild type (WT). Under HT, oslac12 mutants showed significantly lower seedling survival rates (~13-22%) than WT (~43%), whereas OE lines displayed higher survival rates (~68-74%). At the heading stage, OsLAC12 overexpression lines activated the antioxidant enzyme system in spikelets, regulate

SUBMITTER: Ding S 

PROVIDER: S-EPMC12473251 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature