Cross-Scanner Harmonization of AI/DL Accelerated Quantitative Bi-Parametric Prostate MRI.

ABSTRACT: Clinical application of AI/DL-aided acquisitions for quantitative bi-parametric (q-bp)MRI requires validation and harmonization across vendor platforms. An AI/DL-accelerated q-bpMRI, including 5-echo T₂ and 4-b-value apparent diffusion coefficient (ADC) mapping, was implemented on two 3T clinical scanners by two vendors alongside the qualitative standard-of-care (SOC) MRI protocols for six patients with biopsy-confirmed prostate cancer (PCa). AI/DL versus SOC bpMRI image quality was compared for MR-visible PCa lesions on a 4-point Likert-like scale. Quantitative validation and protocol bias assessment were performed using a multiparametric phantom with reference T₂ and diffusion kurtosis values mimicking prostate tissue ranges. Six-minute q-bpMRI achieved acceptable d

SUBMITTER: Malyarenko D 

PROVIDER: S-EPMC12473519 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature