Nurse-Led Interventions to Improve Health, Adherence, and Functional Outcomes in Adults and Older Adults With Multimorbidity: A Systematic Review of Randomized and Quasiexperimental Studies.

ABSTRACT: Objective: To synthesize evidence from randomized controlled trials (RCTs) and quasiexperimental studies evaluating the effectiveness of nurse-led interventions on health outcomes in adults and older adults with multimorbidity. Background: Multimorbidity presents complex healthcare challenges and worsened outcomes, especially in older adults. Nurse-led interventions are emerging as a strategic model to address these needs. Evaluating their effectiveness is essential for advancing evidence-based chronic care. Design: A systematic review guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. Methods: Two reviewers independently screened studies according to refined inclusion criteria. Risk of bias was assessed using the Risk of

SUBMITTER: Ruksakulpiwat S 

PROVIDER: S-EPMC12473742 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature