The Passive Immunoprotective Activity Using Egg Yolk IgY Antibodies of Live or Inactivated <i>Aeromonas veronii</i> Against Major Pathogenic Bacteria (<i>A. veronii</i> and <i>A. hydrophila</i>) in Fish.

ABSTRACT: Egg yolk immunoglobulin Y (IgY) has significant application potential in aquaculture as passive immunotherapy against various bacterial infections owing to its capacity for large-scale and cost-effective production. In this study, IgY antibodies of live or inactivated Aeromonas veronii were generated by laying hens immunization. Subsequently, passive immune protection experiments of the two IgY antibodies were conducted on goldfish (Carassius auratus) infected with A. veronii and Aeromonas hydrophila. The results indicated that both live and inactivated bacteria IgY antibodies provided significant passive protection rates (p < 0.05). Furthermore, ELISA tests demonstrated that the two IgY antibodies, as well as the serum of C. auratus, interacted wi

SUBMITTER: Chen J 

PROVIDER: S-EPMC12474119 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature