Effects of Supplementation with Chlorogenic Acid-Rich Extract from <i>Eucommia ulmoides</i> Oliver During Peri-Implantation on the Reproductive Performance and Gut Microbiota of Sows.

ABSTRACT: Chlorogenic acid (CGA)-rich extracts from Eucommia ulmoides Oliver (CAE) are known for their gut health and antioxidant benefits in livestock. This study examines the effects of CAE supplementation during the peri-implantation period on sow reproductive performance and the gut microbiota. Sixty Dongliao black sows were randomized to receive either no supplementation (control) or CAE at 600 or 2000 mg/kg daily from gestation day -5 through day 15. High-dose CAE intake significantly increased total antioxidant capacity (T-AOC), superoxide dismutase (SOD), catalase (CAT), immunoglobulin A (IgA), and immunoglobulin M (IgM) levels in sow serum but decreased malondialdehyde (MDA) levels. Fecal short-chain fatty acids (SCFAs) also increase significantly. These changes correlate with improv

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC12474264 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature