Effects of ZnFe₂O₄ Nanoparticles on Development and Rhythmic Behavior of <i>Drosophila melanogaster</i>.

ABSTRACT: Objectives: This study planned to determine the biological effects associated with ZnFe₂O₄-NPs exposure using Drosophila melanogaster as an in vivo model. Methods: ZnFe₂O₄-NPs were hydrothermally synthesized, and the development of offspring flies were evaluated via dietary exposure to different doses of ZnFe₂O₄-NPs (0, 200, 400, 600 μg/mL). Rhythmic behaviors of parent male flies were monitored. Results: Internalization of ZnFe₂O₄-NPs through the intestinal barrier occurred. Oral intake of ZnFe₂O₄-NPs decreased the eclosed adult numbers and perturbed the insect developmental process. In male flies, significant upregulation of HSPs and Turandot family ge

SUBMITTER: Yan W 

PROVIDER: S-EPMC12474399 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature