Grading the strength and certainty of the scientific evidence of the bidirectional association between periodontitis and noncommunicable diseases: an umbrella review.

ABSTRACT:

Objective

Periodontitis and various noncommunicable diseases (NCDs) have been proposed to have a bidirectional relationship. The purpose of this umbrella review is (1) to synthesize the evidence and (2) to grade the strength and certainty of the scientific evidence regarding the bidirectional association between periodontitis and NCDs.

Data sources

Electronic databases were systematically searched from January 2021 and July 2024; MEDLINE (via PubMed), Embase and SciELO.

Data selection and extraction

Potential epidemiologic systematic reviews with meta-analysis that studied the bidirectional association between periodontitis and NCDs were identified by two independent reviewers and filtered by title and abstract according to the selection criteria. The strength and the

SUBMITTER: Rodriguez-Medina C 

PROVIDER: S-EPMC12474539 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature