Five Data-Informed Principles for Advancing Inclusive Research in Clinical Trials: A Pharma Perspective.

ABSTRACT: Advancing inclusive research (AIR) in clinical trials requires frameworks and metrics for assessing real-world data and measuring population science. Because different factors drive health inequities and variables in measuring population science, relying on one metric for measuring progress may have limitations. Five principles (5Ps) are proposed for AIR globally that form the basis for a data-informed framework to measure and systematically define inclusive research to ensure rigor and benchmarking within organizations and across the broader sector. The first principle addresses biological, genetic, and population science considerations and their responsible use as data elements. The second principle pertains to using data to inform global region, country, and site placement, which includ

SUBMITTER: James SL 

PROVIDER: S-EPMC12474690 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature