Non-invasive goal-directed fluid therapy with the pleth variability index (PVI): a systematic review and meta-analysis.

ABSTRACT: Optimal intraoperative fluid management is essential to improve surgical outcomes and reduce complications. The Pleth Variability Index (PVI), a dynamic and non-invasive indicator of fluid responsiveness, has been proposed as a tool for goal-directed fluid management. This systematic review and meta-analysis aimed to evaluate the effectiveness of PVI-guided fluid therapy compared to conventional fluid management (CFM) in non-cardiac surgeries. A comprehensive search of PubMed, Embase, and Cochrane databases up to January 2024 identified eligible studies. Primary outcomes included total intraoperative fluid volume and crystalloid administration. Secondary outcomes included hemodynamic parameters, renal function markers, acid-base balance, and hospital length of stay (LOS). Random-effects mo

SUBMITTER: Felippe VA 

PROVIDER: S-EPMC12474725 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature