Associations between patient-reported vision impairment in low luminance and vision-related quality of life in intermediate age-related macular degeneration.

ABSTRACT: Intermediate age-related macular degeneration (iAMD) reduces vision under low-luminance conditions, affecting quality of life (QoL). The Vision Impairment in Low Luminance (VILL) questionnaire captures QoL domains relevant in iAMD but most AMD studies use the generic vision-related QoL measure Visual Function Questionnaire (NEI VFQ). To investigate associations between these generic and specific vision-related QoL instruments, and explore the added value of including the VILL over the NEI VFQ in future iAMD studies, we analysed cross-sectional study data from individuals with iAMD. Associations were investigated using age-adjusted regression models. We included 150 participants (73% women, 74.6 ± 7.8 years). VILL subscale scores were associated with NEI VFQ scores (p ≤ 0.014) and explained

SUBMITTER: Terheyden JH 

PROVIDER: S-EPMC12474979 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature