Comparison of low vs high tidal volumes in one-lung ventilation during thoracic surgery: a propensity-weighted cohort study.

ABSTRACT: The optimal tidal volume (TV) during one-lung ventilation (OLV) for thoracic surgery remains uncertain. This study aimed to evaluate the association between intraoperative tidal volume and the incidence of postoperative respiratory complications in patients undergoing thoracic surgery. We conducted a post-hoc analysis of single-center observational cohort study who underwent elective thoracic surgery with OLV between January 2015 and January 2021. Patients were categorized according to their mean intraoperative TV: < 5 mL/kg versus ≥ 5 mL/kg predicted body weight (PBW). The primary outcome was postoperative respiratory complications (PRCs) within 7 days. Secondary outcomes included other major complications and 30-/90-day mortality. Analyses were adjusted using propensity score overlap wei

SUBMITTER: Braik R 

PROVIDER: S-EPMC12475042 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature