Clinical application value of erythroferrone (ERFE) and hepcidin in pregnant women with thalassemia and iron-deficiency anemia: a comprehensive study.

ABSTRACT: To explore the metabolic levels of ERFE (Erythroferrone) and Hepcidin in pregnant women with thalassemia combined with iron deficiency anemia (IDA), and to analyze the differences in serum ERFE, Hepcidin levels and iron-related indicators before and after iron supplementation in these pregnant women, providing a theoretical basis and effective monitoring indicators for the clinical iron supplementation treatment of pregnant women with thalassemia combined with IDA. The experimental groups comprised:50 thalassemia-monotherapy cases (THAL group), 54 thalassemia with iron-deficiency anemia cases (THAL-IDA group),50 iron-deficiency anemia cases (IDA group).All cases were diagnosed between April 2023 and September 2024, with 50 healthy pregnant women from the same period serving as controls (NC

SUBMITTER: Huang N 

PROVIDER: S-EPMC12475275 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature