Size distribution and viral RNA load of influenza virus-laden airborne particles emitted from pigs over the course of an H1N1 infection.

ABSTRACT: Airborne influenza infections cause significant disease in animals and people. However, there is limited information on the dynamics of viral emissions and size distribution of airborne virus-laden particles generated by infected animals. In this study, we used pigs as a model for the airborne transmission of influenza A virus (IAV) and we quantified nasal shedding, viral RNA load of airborne particles emitted from pigs experimentally infected with a swine-origin H1N1 IAV, and characterized the size distribution of the virus-laden particles generated from infected pigs over the course of infection. We found that the peak of nasal shedding and airborne IAV-laden particles across multiple size ranges took place at 2 days post inoculation (DPI), with higher viral RNA load found in larger part

SUBMITTER: Wang L 

PROVIDER: S-EPMC12475501 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature