Novel TA-IVIZ Patch and BSS Tamponade for Macular Hole Repair: A Pilot Study.

ABSTRACT:

Purpose

This study evaluates the efficacy of minimal vitrectomy for full-thickness macular hole (FTMH) repair using a triamcinolone acetonide (TA)-IVIZ patch and balanced salt solution (BSS) tamponade.

Methods

An in vitro experiment was conducted to compare the adhesiveness and stability of the TA-IVIZ patch and the TA-DisCoVisc patch. Although the clinical arm of the study was a prospective study, an interventional cohort study was then performed on 24 eyes from 23 consecutive patients with FTMH. All eyes underwent minimal vitrectomy combined with internal limiting membrane (ILM) peeling, an inverted ILM flap, TA-IVIZ patch application, and BSS tamponade, without postoperative prone positioning. Outcomes, including anatomical closure rate, best-corrected visual acuity, and

SUBMITTER: Shen Y 

PROVIDER: S-EPMC12476159 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature