Cognitive stimulation in Parkinson's disease with mild cognitive impairment.

ABSTRACT:

Background

Cognitive impairment is among the most frequent and disabling non-motor symptoms of Parkinson's disease (PD), often emerging early and substantially impacting autonomy and quality of life. While cognitive stimulation (CS) is supported in other neurodegenerative conditions, its role in PD is less explored. This study aimed to compare the efficacy of a therapist-guided, home-based CS program, delivered via a virtual reality rehabilitation system, with a conventional in-person CS intervention.

Methods

Of 123 individuals screened, 45 patients with PD and mild cognitive impairment (PD-MCI) were randomized to either the tele-rehabilitation group (TRG; n = 25) or the control group (CG; n = 20). Both groups received the same standardized 4-week CS program (20 multi-domain

SUBMITTER: Buonocore J 

PROVIDER: S-EPMC12476383 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature