The interplay between perceived fatigability, intrinsic capacity, and physical activity: network analysis in a British birth cohort study.

ABSTRACT:

Background

Fatigability-an individual's susceptibility to fatigue when performing standardized activities-may arise from diminished functional reserves and contribute to reduced physical activity (PA) levels, potentially reinforcing the disablement process. In this study, we used network analysis to examine the associations among physical and mental fatigability, different domains of intrinsic capacity (IC), and PA. Additionally, we investigated whether fatigability mediates the association between IC and PA.

Methods

We ran analyses of cross-sectional data on participants from the MRC National Survey of Health and Development at age 68-69 years (n = 1537). Physical and mental fatigability were assessed using the Pittsburgh Fatigability Scale, and PA was self-reported. We qua

SUBMITTER: Koivunen K 

PROVIDER: S-EPMC12476581 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature