Non-coding RNAs as diagnostic biomarkers for preeclampsia: a systematic review and meta-analysis.

ABSTRACT:

Background

Preeclampsia (PE), a grave obstetric complication, mandates the expeditious formulation of efficacious early diagnostic strategies. Accumulating evidence suggests that non - coding RNAs (ncRNAs), which are present in maternal circulation and placental tissues, display abnormal expression patterns in patients with PE, underscoring their potential as diagnostic biomarkers. This systematic review and meta - analysis intends to assess the diagnostic accuracy of ncRNAs for the detection of PE.

Methods

A comprehensive search was carried out across seven databases (China National Knowledge Infrastructure [CNKI], Wanfang Database, VIP Database, PubMed, Web of Science, Embase, and the Cochrane Library) up to December 25, 2024, to identify case - control and cohort studies

SUBMITTER: Liu J 

PROVIDER: S-EPMC12476626 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature