Safety and effectiveness of apixaban use for stroke prevention during Ramadan fasting (the API-RAM study).

ABSTRACT:

Introduction

Patients receiving anticoagulation for atrial fibrillation (AF) are required to consult their doctor before starting Ramadan fasting to get their authorization for fasting and adapt their treatment. More often, a once-daily regimen is proposed to facilitate their intake schedule. Apixaban, a direct oral anticoagulant, prescribed twice daily with an optimal benefit/risk ratio in numerous situations, has very limited data regarding its use during Ramadan.

Aim

The aim of this study was to evaluate the safety and the efficacy of apixaban for stroke prevention in AF patients during the month of Ramadan.

Methods

An observational, multicentric study was performed in Tunisia during two consecutive years during the specific month of Ramadan. The API-RAM study incl

SUBMITTER: Ghrab A 

PROVIDER: S-EPMC12476992 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature