Associations between longitudinal changes in sleep stages and risk of cognitive decline in older men.

ABSTRACT:

Study objectives

To investigate the relationships between longitudinal changes in sleep stages and the risk of cognitive decline in older men.

Methods

This study included 978 community-dwelling older men who participated in the first (2003-2005) and second (2009-2012) sleep ancillary study visits of the Osteoporotic Fractures in Men Study. We examined the longitudinal changes in sleep stages at the initial and follow-up visits, and the association with concurrent clinically relevant cognitive decline during the 6.5-year follow-up.

Results

Men with low to moderate (quartile 2, Q2) and moderate increase (Q3) in N1 sleep percentage had a reduced risk of cognitive decline on the modified mini-mental state examination compared to those with a substantial increase (Q4) in N

SUBMITTER: Wang Q 

PROVIDER: S-EPMC12477118 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature