Caffeine on the mind: EEG and cardiovascular signatures of cortical arousal revealed by wearable sensors and machine learning-a pilot study on a male group.

ABSTRACT:

Introduction

Caffeine is the most widely consumed psychoactive substance, and its stimulant properties are well documented, but few investigations have examined its acute effects on brain and cardiovascular responses during cognitively demanding tasks under ecologically valid conditions.

Method

This study used wearable biosensors and machine learning analysis to evaluate the effects of moderate caffeine (162 mg) on heart rate variability (HRV), entropy, pulse transit time (PTT), blood pressure, and EEG activity. Twelve healthy male participants (20-30 years) completed a within-subjects protocol with pre-caffeine and post-caffeine sessions. EEG was recorded from seven central electrodes (C3, Cz, C4, CP1, CP2, CP5, CP6) using the EMOTIV EPOC Flex system, and heart rate (HR) an

SUBMITTER: Chowdhury S 

PROVIDER: S-EPMC12477153 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature