Randomized, non-inferiority clinical trial of three topical dermatophytosis treatments in shelter cats.

ABSTRACT: ObjectivesTopical treatments, along with systemic oral antifungals, are the mainstay of infection and environmental control for cats with dermatophytosis in animal shelters. This study aimed to provide realistic expectations of the performance of three commonly used topical treatments to help shelters minimize the length of stay and optimize feline welfare.MethodsA prospective, randomized, semi-blinded clinical trial compared treatment success and time to cure for miconazole chlorhexidine (MC) and hydrogen peroxide (HP) shampoos vs lime sulfur (LS) using a non-inferiority model. Cats with Microsporum canis were enrolled at four US animal shelters, treated with oral itraconazole and randomized into three topical treatment groups. Treatment success was defined as mycological cure by 7

SUBMITTER: DeTar L 

PROVIDER: S-EPMC12477372 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature