Efficacy and safety of Shouhui Tongbian Capsules, a traditional Chinese medicine, combined with 2L polyethylene glycol for bowel preparation before colonoscopy: a multicenter, randomized, single-blind, parallel-controlled clinical trial.

ABSTRACT:

Background

High-volume polyethylene glycol (PEG) solutions are commonly used for bowel preparation but are often poorly tolerated, reducing patient compliance. Shouhui Tongbian Capsules (SHTBC), a traditional Chinese medicine known to promote gastrointestinal motility, may offer an alternative approach. However, its role in bowel preparation remains unclear.

Objectives

To evaluate the efficacy, safety, and tolerability of a novel bowel preparation regimen combining SHTBC with low-volume PEG (2L) compared to conventional high-volume PEG (3L).

Design

Multicenter, randomized, single-blind, parallel-controlled trial.

Methods

A total of 404 participants scheduled for colonoscopy across 34 medical centers in China were randomized into two groups: the experimental gro

SUBMITTER: Ye F 

PROVIDER: S-EPMC12477385 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature